Rebirth of the God-level Xueba

"Genomics" illuminates the way for the brave and is changing the ecology of the field of genetics. The cowardly may fear today's genomics, just like they feared genetics back then, but, gentlemen and ladies, genomes Learning has taken a step forward, we either follow it, or we can only look at it from a distance..." Linden’s explanation is simple and vivid, with the flavor of American movies in the 1970s.

But to the Chinese, this way of speaking is both familiar and American, and they can’t help but applaud.

Applauding for the friends from the United States, everyone worked hard.

Director Ma also applauded vigorously, especially after Yang Rui stepped onto the stage.

"Thank you Mr. Linden." Yang Rui took the microphone, smiled, and said: "Thank you Norton Press for the invitation to let us get together today. Because it is a gathering organized by a publishing house from the United States, we will temporarily follow the American rules. Bylaws, let’s not ask the leaders to speak..."

There was a burst of laughter from below. For the current Chinese, especially civil servants and officials, the degree of such a joke is very deep.

Yang Rui smiled again, grabbed the "Genomics" on the small stage, and showed it to everyone, saying: "I want to talk about genomics, or more precisely, the development of genomics. As we all know, modern genes The research focus of science and biology is related to structure. In other words, what we currently hope and need to know is structure, the structure of genes, the structure of proteins, and the structure of cells. The article that I have seen most on "is currently a hot spot, but..."

"Foresightedly speaking, structural studies should not be our focus. Of course, we still need to study structure, but research structure should not be the focus, nor should it be a hot spot..."

"What are the key points and hot spots? I think it should be a function not to fall in love with treacherous ministers!"

"Functional genomes, functional proteins and functional cells are our goals, focus and hot spots. This is also the main reason why I wrote "Genomics"..." Yang Rui's topic was very high and his eyes were deep.

He has reason to prove with deep eyes, because the speech he is giving is indeed important.

Yang Rui is tantamount to predicting the arrival of the post-genomic era. The genome here originally referred to the Human Genome Project, which means the future biology of the Human Genome Project.

However, if the post-genome era of the Human Genome Project is replaced with the post-genome era after "Genomics", there seems to be no big problem.

The crux of the problem lies in the fact that the functional genome replaces the structural genome.

"Genomics" was originally the theoretical guidance for the Human Genome Project.

In short, "Genomics" is equivalent to architectural design, and the Human Genome Project is actually engineering construction.

Yang Rui naturally wanted to take this opportunity to brush his face more.

The prediction of no money may not make much sense to ordinary people, but it has great value in the scientific community.

Yang Rui has done such a thing before, and the benefits are also very high.

Therefore, he couldn't help but prepare to do it again.

Just like astronomers predicting black holes, biologists predicting success in the post-genome era will also have a reputation.

Yang Rui hopes that his "Genomics" can take advantage of the post-genome predictions to soar into the sky. When that happens, when people talk about the post-genome era, they will naturally mention Yang Rui's "Genomics".

It is even possible to call "Genomics" the theoretical guidance of the entire post-genome era.

The so-called big cow who can't get around stands up step by step, like a technical barrier. You have to stack one brick on top of another and put cement in the middle to make it more stable.

Just like Newton, if you just get a Newton Leibniz equation, this brick is very strong and tight, and it is enough for Newton and Leibniz to be called the darling of the times, but after all, it is not Newton. Adding the brick of integral algebra, it is different. This is an important step in turning mathematics from the subject of perception to the subject of thinking, and is the founder of the true natural sciences.

Of course, if only this is the case, Newton is still not a Newton, that is, coupled with analytic geometry and polar coordinates, coupled with "Cubic Curve" and "Generalized Arithmetic", he is not the Newton in people's impression, but can only be said to be a Newton. The great mathematician, and the little prince Gauss, the great emperor Olazi side.

The reason why Newton is Newton lies in the great wall he built, Newton’s mechanics composed of Newton’s three laws, the law of universal gravitation, the law of planets, and the law of optics... So, in the end, he kept pace with him. It's Einstein...

"Genomics" is Yang Rui's first book, and it is a very representative brick. Yang Rui has spent a lot of thought on this and extended his speech to 15 minutes.

Of course, in terms of domestic speeches, this is nothing.

It is a little pity that no more than a quarter of the people present can understand what he is talking about.

But Yang Rui didn’t care. This speech was not just for the audience at the scene. It was like the speech at the secretary’s office meeting was not just for chatting with other people in the meeting, or the report at an academic report meeting It's not just a cold dictatorship for the scholars present (the king of the net).

The post-genomic era will not be realized today, nor will it be realized tomorrow, but one day in the future, when the era when functional genomics research gradually replaces structural genomics really comes, today’s speech will be of extraordinary significance. .

Just as patents are not meant to take effect at that time, and patent barriers are not meant to deter patent thieves today.

However, the scholars who understand, mainly those from the invited universities and research institutes, still listen very carefully.

The concept of the post-genome era is actually very simple. In layman's terms, it is to replace structure with function.

The so-called functional genome is to investigate the function of a genome, such as the existence of a leg-shaking gene. Its function is to shake the leg. If the m gene exists, its function is to shake the m. As for its structure, for biology, although It still has great significance, but from a broader perspective, the meaning is not as great as the function.

In the final analysis, it's like Yang Rui said, who is more important. It's not that structure is not important, but function is more important.

In the past few years, people didn’t have the prerequisites to make functional genomes, so everyone was doing structural genomes. However, with genomics and the human genome project, structural genomes should give way to functional genomes. Up.

A quarter of an hour later, when Yang Rui's speech was over, someone immediately raised his hand.

"This... we are not holding an academic report meeting." Linden of Norton Press stood up and smiled and said, "We are not preparing for the defense session."

"Just one question." The man who raised his hand was a 30-year-old academic man wearing glasses.

Linden hesitated and said, "Just one question, please."

"I want to say that we must first understand the structure before we can understand the function. Moreover, studying the structure first has another advantage. We can know the unknown function of an unfamiliar structure through the same or similar structure..."

"I prefer to call what you are talking about as comparative functional genomics." Yang Rui shrugged and said: "Based on the genome map and sequence determination, compare known genes and genome structures to understand the functions of genes. And expression mechanism, this will be the focus of development in the next few years, but what I want to say is the ultimate direction. Our ultimate goal is to use the information provided by structural genomics to develop and apply experimental methods. At the system level, To study the function of the genome, so as to expand the research object from a single gene and protein study to the joint action of multiple genes and proteins..."

The academic man with glasses tilted his head and said, "Your end is too far away. How many years, 50, 100 years will it take?"

"How about 15 years." Yang Rui said: "At most 25 years, we will fully enter the era of functional genomics."

"How is it possible." The academic man with glasses smiled: "We have to do structural genomics first, all genes and proteins, how many years will it take? Even if only 50%, or 30%, 50 years are not enough..."

"It is not necessary to complete the structure of all genes and proteins. 30% is also unnecessary. In fact, the human genome project should be launched immediately. Fifteen years' time is enough for us to understand the structure of genes clearly." Yang Rui smiled. Put down the microphone and gestured to Linden.

Linden immediately stepped onto the stage and ended the topic with a smile: "Now, please let us welcome our guests..."

The boring leader's speech began, and the academic man with glasses couldn't ask if he wanted to.

Director Ma waited for Yang Rui to sit on the chair, and said with a smile: "The one who asked the question just now doesn't seem to be convinced yet."

Yang Rui glanced back, and if the academic man with glasses was really upset, he hadn't said enough. If it weren't for seriousness, he might run over now, or just stand up and shouted the bone debt.

"There is no way you are not convinced." Yang Rui smiled and said, "It wasn't for him."

"how to say?"

"This is a prophecy. The prophecy is discussed before it is realized. I don't think it is necessary." Yang Rui said simply.

"I disdain to explain." Director Ma saw through, he was too familiar with Yang Rui's expression.

Yang Rui didn't explain, but smiled softly.

"Speaking of, Xiao Yang, let me call you that, what does your family do." Director Ma looked like a good elder.

"Oh, my father used to be the secretary of the township party committee, and now he has been transferred to the China Merchants Bureau." Yang Rui didn't hide anything, it was all public information.

Director Ma nodded "Oh" and said with a smile: "China Merchants? It's a system with the Commercial Bureau. I'm quite familiar with this one."

"You are not from the Ministry of Education?"

"You know when you meet frequently, you know, what is often signed between ministries and commissions, I often go to the Ministry of Commerce to sign off." Cooperation between departments often requires the signature of the leaders of different departments, which is called a countersign, and a sign off is a reminder. Signed. The chiefs of the central ministries and commissions have heavy powers and responsibilities, which are also related to this.

Yang Rui said casually: "Does the Ministry of Education and the Ministry of Commerce still have frequent contacts?"

"Nowadays, who doesn't want to deal with the Ministry of Commerce." Director Ma laughed and said: "Fortunately, I am in the Ministry of Education. If it is the Bureau of Education, I would be embarrassed to run into the Ministry of Commerce."

Having said this, Director Ma stopped and said, "Speaking of which, I do have a few friends in the Ministry of Commerce, who are also senior intellectuals. Maybe you have something to talk about. I will make an appointment someday and talk together. chat."

"Okay." Yang Rui casually said.

Chief Ma didn't see it this time, he just felt that he was almost ready, and he gestured to the back with his eyes.

The man who bit his ears with Director Ma immediately stood up and laughed, "Yang Rui, you are lucky. Director Ma likes to promote young people most."

"Thank you Director Ma." What can Yang Rui say, I can't say, I don't need your promotion.

The man sitting on the right side of Director Ma, he came over to the ****, with a beard and charming smile, and said: "Yang Rui, at this time, you can't be shy. Do you know what Director Ma is in charge of? "

"What's the matter?"

"Leave aside, the review of the university's textbooks will be in the hands of Director Ma." The shaggy charming man put his chin on his hand and blinked at Yang Rui.

Yang Rui was stunned. He didn't expect that the man next to him could actually promote him. He can only say that the responsibilities of the Chinese government are so comprehensive.

"If your book can be included in the university's designated textbooks, that is, the catalog of reference books, you can sell a lot more." The charming man continued to increase.

Yang Rui nodded. More than just selling a lot more, there are so many domestic colleges and universities, if it can be included in the teaching materials, the purchase volume of the library alone can blow up the sales in the United States. Each student has one copy, and no matter how cheap the price is. Publishers and authors earn money, and it’s no wonder that Director Ma will be invited by Norton Press to attend today’s publication briefing and sit next to him.

"Director Ma, please advise." The county magistrate is not as good as the current one, and Yang Rui's smile is also much sincere.

"Okay, I like to teach young people the most. Let's have a good chat someday when I have time." Director Ma said, handing Yang Rui a business card and asking Yang Rui to find himself. Naturally, he was more imposing than when he asked Yang Rui.

…